4JRN

ROP18 kinase domain in complex with AMP-PNP and sucrose

Summary for 4JRN

Entry DOI	10.2210/pdb4jrn/pdb
Related PRD ID	PRD_900003
Descriptor	Rhoptry kinase family protein, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
Functional Keywords	protein kinase, kinase, membrane, transferase
Biological source	Toxoplasma gondii
Total number of polymer chains	1
Total formula weight	42403.27
Authors	Lim, D.,Gold, D.A.,Lindsay, J.,Rosowski, E.E.,Niedelman, W.,Yaffe, M.B.,Saeij, J.P.J. (deposition date: 2013-03-21, release date: 2013-10-23, Last modification date: 2020-07-29)
Primary citation	Lim, D.,Gold, D.A.,Julien, L.,Rosowski, E.E.,Niedelman, W.,Yaffe, M.B.,Saeij, J.P. Structure of the Toxoplasma gondii ROP18 kinase domain reveals a second ligand binding pocket required for acute virulence. J.Biol.Chem., 288:34968-34980, 2013 Cited by PubMed: 24129568 DOI: 10.1074/jbc.M113.523266 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.71 Å)

Structure validation