4JRB

Structure of Cockroach Allergen Bla g 1 Tandem Repeat as a EGFP fusion

4JRB の概要

• エントリーDOI: 10.2210/pdb4jrb/pdb
• 分子名称: Green fluorescent protein, CHLORIDE ION, (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ... (5 entities in total)
• 機能のキーワード: allergen, asthma, new fold, proposed lipid binding protein, lipid binding protein
• 由来する生物種: Aequorea victoria (Jellyfish); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48582.76

構造登録者

Mueller, G.A.,Pedersen, L.C.,Lih, F.B.,Glesner, J.,Moon, A.F.,Chapman, M.D.,Tomer, K.,London, R.E. (登録日: 2013-03-21, 公開日: 2013-07-24, 最終更新日: 2024-10-16)

主引用文献

Mueller, G.A.,Pedersen, L.C.,Lih, F.B.,Glesner, J.,Moon, A.F.,Chapman, M.D.,Tomer, K.B.,London, R.E.,Pomes, A.
The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment.
J.Allergy Clin.Immunol., 132:1420-1426.e9, 2013

PubMed Abstract: Sensitization to cockroach allergens is a major risk factor for asthma. The cockroach allergen Bla g 1 has multiple repeats of approximately 100 amino acids, but the fold of the protein and its biological function are unknown.

PubMed: 23915714
DOI: 10.1016/j.jaci.2013.06.014

実験手法

X-RAY DIFFRACTION (2.414 Å)