4JQU
Crystal structure of Ubc7p in complex with the U7BR of Cue1p
Summary for 4JQU
Entry DOI | 10.2210/pdb4jqu/pdb |
Descriptor | Ubiquitin-conjugating enzyme E2 7, Coupling of ubiquitin conjugation to ER degradation protein 1, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total) |
Functional Keywords | ubc7p:u7br complex, ligase-activator complex, ligase-protein binding complex, ligase/protein binding |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: Q02159 Endoplasmic reticulum membrane ; Single-pass membrane protein : P38428 |
Total number of polymer chains | 2 |
Total formula weight | 25671.37 |
Authors | Liang, Y.-H.,Metzger, M.B.,Weissman, A.M.,Ji, X. (deposition date: 2013-03-20, release date: 2013-05-29, Last modification date: 2023-09-20) |
Primary citation | Metzger, M.B.,Liang, Y.H.,Das, R.,Mariano, J.,Li, S.,Li, J.,Kostova, Z.,Byrd, R.A.,Ji, X.,Weissman, A.M. A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms. Mol.Cell, 50:516-527, 2013 Cited by PubMed: 23665230DOI: 10.1016/j.molcel.2013.04.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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