4JQU

Crystal structure of Ubc7p in complex with the U7BR of Cue1p

4JQU の概要

• エントリーDOI: 10.2210/pdb4jqu/pdb
• 分子名称: Ubiquitin-conjugating enzyme E2 7, Coupling of ubiquitin conjugation to ER degradation protein 1, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• 機能のキーワード: ubc7p:u7br complex, ligase-activator complex, ligase-protein binding complex, ligase/protein binding
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• 細胞内の位置: Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: Q02159; Endoplasmic reticulum membrane ; Single-pass membrane protein : P38428
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 25671.37

構造登録者

Liang, Y.-H.,Metzger, M.B.,Weissman, A.M.,Ji, X. (登録日: 2013-03-20, 公開日: 2013-05-29, 最終更新日: 2023-09-20)

• 主引用文献: Metzger, M.B.,Liang, Y.H.,Das, R.,Mariano, J.,Li, S.,Li, J.,Kostova, Z.,Byrd, R.A.,Ji, X.,Weissman, A.M.; A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms.; Mol.Cell, 50:516-527, 2013; PubMed: 23665230; DOI: 10.1016/j.molcel.2013.04.004

実験手法

X-RAY DIFFRACTION (1.81 Å)