4JMY
Crystal structure of HCV NS3/NS4A protease complexed with DDIVPC peptide
Summary for 4JMY
Entry DOI | 10.2210/pdb4jmy/pdb |
Descriptor | Polyprotein, HCV non-structural protein 4A, substrate peptide, ... (6 entities in total) |
Functional Keywords | hepatitis c virus, serine protease, ddivpc, hydrolase-protein binding complex, hydrolase/protein binding |
Biological source | Hepatitis C virus genotype 2 More |
Total number of polymer chains | 6 |
Total formula weight | 44456.10 |
Authors | Lemke, C.T. (deposition date: 2013-03-14, release date: 2013-10-30, Last modification date: 2024-02-28) |
Primary citation | LaPlante, S.,Lemke, C.T. Importance of the peptide scaffold of drugs that target the hepatitis C virus NS3 protease and its crucial bioactive conformation and dynamic factors. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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