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4JHW

Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25

Summary for 4JHW
Entry DOI10.2210/pdb4jhw/pdb
Related4JHA
DescriptorD25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0 (3 entities in total)
Functional Keywordsimmunoglobulin; type i fusion protein, membrane fusion, immune system
Biological sourceHomo sapiens
More
Cellular locationVirion membrane; Single-pass type I membrane protein: P03420
Total number of polymer chains3
Total formula weight102715.94
Authors
Primary citationMcLellan, J.S.,Chen, M.,Leung, S.,Graepel, K.W.,Du, X.,Yang, Y.,Zhou, T.,Baxa, U.,Yasuda, E.,Beaumont, T.,Kumar, A.,Modjarrad, K.,Zheng, Z.,Zhao, M.,Xia, N.,Kwong, P.D.,Graham, B.S.
Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340:1113-1117, 2013
Cited by
PubMed: 23618766
DOI: 10.1126/science.1234914
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.6 Å)
Structure validation

217705

數據於2024-03-27公開中

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