4JHW
Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25
Summary for 4JHW
Entry DOI | 10.2210/pdb4jhw/pdb |
Related | 4JHA |
Descriptor | D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0 (3 entities in total) |
Functional Keywords | immunoglobulin; type i fusion protein, membrane fusion, immune system |
Biological source | Homo sapiens More |
Cellular location | Virion membrane; Single-pass type I membrane protein: P03420 |
Total number of polymer chains | 3 |
Total formula weight | 102715.94 |
Authors | Mclellan, J.S.,Chen, M.,Leung, S.,Graepel, K.W.,Du, X.,Yang, Y.,Zhou, T.,Baxa, U.,Yasuda, E.,Beaumont, T.,Kumar, A.,Modjarrad, K.,Zheng, Z.,Zhao, M.,Xia, N.,Kwong, P.D.,Graham, B.S. (deposition date: 2013-03-05, release date: 2013-05-01, Last modification date: 2023-09-20) |
Primary citation | McLellan, J.S.,Chen, M.,Leung, S.,Graepel, K.W.,Du, X.,Yang, Y.,Zhou, T.,Baxa, U.,Yasuda, E.,Beaumont, T.,Kumar, A.,Modjarrad, K.,Zheng, Z.,Zhao, M.,Xia, N.,Kwong, P.D.,Graham, B.S. Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science, 340:1113-1117, 2013 Cited by PubMed: 23618766DOI: 10.1126/science.1234914 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
Download full validation report