4JHQ

Crystal structure of avidin - 6-(6-biotinamidohexanamido)hexanoylferrocene complex

Summary for 4JHQ

• Entry DOI: 10.2210/pdb4jhq/pdb
• Related: 1VYO 2AVI 4I60
• Descriptor: Avidin, [(1,2,3,4,5-eta)-cyclopentadienyl][(1,2,3,4,5-eta)-{6-[(6-{[5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl]amino}hexanoyl)amino]hexanoyl}cyclopentadienyl]iron, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: beta barrel, biotin-binding protein, 6-(6-biotinamidohexanamido)hexanoylferrocene, glycoprotein, hen egg white
• Biological source: Gallus gallus (bantam,chickens)
• Cellular location: Secreted: P02701
• Total number of polymer chains: 2
• Total formula weight: 30345.74

Authors

Strzelczyk, P.,Bujacz, A.,Bujacz, G. (deposition date: 2013-03-05, release date: 2013-11-20, Last modification date: 2023-11-08)

• Primary citation: Plazuk, D.,Zakrzewski, J.,Salmain, M.,Blauz, A.,Rychlik, B.,Strzelczyk, P.,Bujacz, A.,Bujacz, G.; Ferrocene-Biotin Conjugates Targeting Cancer Cells: Synthesis, Interaction with Avidin, Cytotoxic Properties and the Crystal Structure of the Complex of Avidin with a Biotin-Linker-Ferrocene Conjugate; Organometallics, 32:5774-5783, 2013; DOI: 10.1021/om4003126

Experimental method

X-RAY DIFFRACTION (1.99 Å)