4JFV

Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(methylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol

Summary for 4JFV

Entry DOI	10.2210/pdb4jfv/pdb
Related	2WVV 4J27 4J28 4JFS 4JFT 4JFU 4JFW
Descriptor	alpha-L-fucosidase, SULFATE ION, IMIDAZOLE, ... (5 entities in total)
Functional Keywords	alpha-l-fucosidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bacteroides thetaiotaomicron
Total number of polymer chains	4
Total formula weight	210996.99
Authors	Wright, D.W.,Davies, G.J. (deposition date: 2013-02-28, release date: 2013-09-18, Last modification date: 2023-09-20)
Primary citation	Hottin, A.,Wright, D.W.,Steenackers, A.,Delannoy, P.,Dubar, F.,Biot, C.,Davies, G.J.,Behr, J.B. alpha-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studies. Chemistry, 19:9526-9533, 2013 Cited by PubMed: 23740878 DOI: 10.1002/chem.201301001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation