4JD9

Contact pathway inhibitor from a sand fly

4JD9 の概要

• エントリーDOI: 10.2210/pdb4jd9/pdb
• 分子名称: 14.5 kDa salivary protein, SULFATE ION (3 entities in total)
• 機能のキーワード: odorant-binding protein, binding protein, glycosaminoglycan, polyphosphate, protein binding
• 由来する生物種: Phlebotomus duboscqi (Sandfly)
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 105866.91

構造登録者

Andersen, J.F.,Xu, X.,Alvarenga, P. (登録日: 2013-02-24, 公開日: 2013-10-16, 最終更新日: 2017-11-15)

• 主引用文献: Alvarenga, P.H.,Xu, X.,Oliveira, F.,Chagas, A.C.,Nascimento, C.R.,Francischetti, I.M.,Juliano, M.A.,Juliano, L.,Scharfstein, J.,Valenzuela, J.G.,Ribeiro, J.M.,Andersen, J.F.; Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate.; Arterioscler Thromb Vasc Biol, 33:2759-2770, 2013; PubMed: 24092749; DOI: 10.1161/ATVBAHA.113.302482

実験手法

X-RAY DIFFRACTION (2.601 Å)