4JD3
Crystal Structure of Mycobacterium tuberculosis PKS11 Reveals Intermediates in the Synthesis of Methyl-branched Alkylpyrones
Summary for 4JD3
Entry DOI | 10.2210/pdb4jd3/pdb |
Related | 4JAO 4JAP 4JAQ 4JAR 4JAT |
Descriptor | Alpha-pyrone synthesis polyketide synthase-like Pks11, PALMITIC ACID, COENZYME A, ... (4 entities in total) |
Functional Keywords | lipid biosynthesis, structural genomics, enzyme function initiative, ketosynthase enzyme, alkylpyrone synthesis, transferase, mycobacterium tuberculosis structural proteomics project, xmtb |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 4 |
Total formula weight | 153221.08 |
Authors | Gokulan, K.,Sacchettini, J.C.,Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) (deposition date: 2013-02-22, release date: 2013-04-24, Last modification date: 2024-02-28) |
Primary citation | Gokulan, K.,O'Leary, S.E.,Russell, W.K.,Russell, D.H.,Lalgondar, M.,Begley, T.P.,Ioerger, T.R.,Sacchettini, J.C. Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. J.Biol.Chem., 288:16484-16494, 2013 Cited by PubMed: 23615910DOI: 10.1074/jbc.M113.468892 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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