4JD3
Crystal Structure of Mycobacterium tuberculosis PKS11 Reveals Intermediates in the Synthesis of Methyl-branched Alkylpyrones
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, B, D) | Alpha-pyrone synthesis polyketide synthase-like Pks11 | polymer | 353 | 37665.1 | 4 | UniProt (O06587) Pfam (PF00195) Pfam (PF02797) UniProt (by SIFTS) (P9WPF3) | Mycobacterium tuberculosis | Alpha-pyrone synthesis polyketide synthase type III Pks11, Chalcone synthase-like protein, CHS-like |
| 2 | E, F, H, J (A, C, B, D) | PALMITIC ACID | non-polymer | 256.4 | 4 | Chemie (PLM) | |||
| 3 | G, I (C, B) | COENZYME A | non-polymer | 767.5 | 2 | Chemie (COA) | |||
| 4 | K, L, M, N (A, C, B, D) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A, C, B, D: 1 - 353 (UniProt: O06587)
| PDB | External Database | Details |
|---|---|---|
| Ser 138 | Cys 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 150660.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2560.8 | |
| All* | Total formula weight | 153221.1 |
