4JAA

Factor inhibiting HIF-1 alpha in complex with consensus ankyrin repeat domain-(d)LEU peptide

Summary for 4JAA

• Entry DOI: 10.2210/pdb4jaa/pdb
• Related: 1H2K 1H2L 1H2M 4B7E 4B7K
• Descriptor: Hypoxia-inducible factor 1-alpha inhibitor, CONSENSUS ANKYRIN REPEAT DOMAIN-(d)LEU, ZINC ION, ... (6 entities in total)
• Functional Keywords: non-heme, 2-oxoglutarate, dioxygenase, oxygenase, dna-binding, metal-binding, transcription, helix-loop-helix-beta, dsbh, facial triad, asparaginyl, aspartyl hydroxylase, epigenetic regulation, signaling, ard, beta-hydroxylation, activator/inhibitor, oxidoreductase-peptide complex, oxidoreductase/peptide
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9NWT6
• Total number of polymer chains: 2
• Total formula weight: 42964.49

Authors

Scotti, J.S.,Ge, W.,McDonough, M.A.,Schofield, C.J. (deposition date: 2013-02-18, release date: 2014-02-19, Last modification date: 2023-11-08)

• Primary citation: Scotti, J.S.,Ge, W.,McDonough, M.A.,Schofield, C.J.; Structure of an oxygenase in complex with substrate; To be Published,

Experimental method

X-RAY DIFFRACTION (2.39 Å)