4J9R

Human DNA polymerase eta-DNA translocated binary complex with TG mispair

Summary for 4J9R

• Entry DOI: 10.2210/pdb4j9r/pdb
• Related: 3MR2 4DL2 4DL3 4J9K 4J9L 4J9M 4J9N 4J9O 4J9P 4J9Q 4J9S
• Descriptor: DNA polymerase eta, DNA (5'-D(*T*AP*CP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*CP*AP*TP*G)-3'), ... (5 entities in total)
• Functional Keywords: immunoglobulin, a to g transition, misincorporation, wobble base pair, dna polymerase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9Y253
• Total number of polymer chains: 3
• Total formula weight: 55093.01

Authors

Zhao, Y.,Gregory, M.,Biertumpfel, C.,Hua, Y.,Hanaoka, F.,Yang, W. (deposition date: 2013-02-16, release date: 2013-05-01, Last modification date: 2023-09-20)

• Primary citation: Zhao, Y.,Gregory, M.T.,Biertumpfel, C.,Hua, Y.J.,Hanaoka, F.,Yang, W.; Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.; Proc.Natl.Acad.Sci.USA, 110:8146-8151, 2013; PubMed: 23630267; DOI: 10.1073/pnas.1303126110

Experimental method

X-RAY DIFFRACTION (2.35 Å)