4J8R
Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment
Summary for 4J8R
Entry DOI | 10.2210/pdb4j8r/pdb |
Descriptor | Light chain of POM2 Fab, Heavy chain of POM2 Fab, Major prion protein, ... (4 entities in total) |
Functional Keywords | immunoglobulin fold, fab, antibody, octapeptide repeat, mouse prion protein, immune system |
Biological source | Mus musculus More |
Cellular location | Cell membrane ; Lipid-anchor, GPI-anchor : P04925 |
Total number of polymer chains | 6 |
Total formula weight | 95912.38 |
Authors | Swayampakula, M.,Baral, P.K.,Kav, N.N.V.,Aguzzi, A.,James, M.N.G. (deposition date: 2013-02-14, release date: 2013-05-22, Last modification date: 2023-09-20) |
Primary citation | Swayampakula, M.,Baral, P.K.,Aguzzi, A.,Kav, N.N.,James, M.N. The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody. Protein Sci., 22:893-903, 2013 Cited by PubMed: 23629842DOI: 10.1002/pro.2270 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.303 Å) |
Structure validation
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