4J5E
Human Cyclophilin D Complexed with an Inhibitor
Summary for 4J5E
Entry DOI | 10.2210/pdb4j5e/pdb |
Related | 4J58 4J59 4J5A 4J5B 4J5C 4J5D |
Descriptor | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, 1-(4-aminobenzyl)-3-{2-[(2R)-2-(2-methoxyphenyl)pyrrolidin-1-yl]-2-oxoethyl}urea (3 entities in total) |
Functional Keywords | isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix : P30405 |
Total number of polymer chains | 1 |
Total formula weight | 18034.58 |
Authors | Gelin, M.,Colliandre, L.,Bessin, Y.,Guichou, J.F. (deposition date: 2013-02-08, release date: 2014-02-19, Last modification date: 2024-02-28) |
Primary citation | Ahmed-Belkacem, A.,Colliandre, L.,Ahnou, N.,Nevers, Q.,Gelin, M.,Bessin, Y.,Brillet, R.,Cala, O.,Douguet, D.,Bourguet, W.,Krimm, I.,Pawlotsky, J.M.,Guichou, J.F. Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7:12777-12777, 2016 Cited by PubMed: 27652979DOI: 10.1038/ncomms12777 PDB entries with the same primary citation |
Experimental method |
Structure validation
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