4J4O

Crystal structure of FK506 binding domain of plasmodium VIVAX FKBP35 in complex with D44

Summary for 4J4O

• Entry DOI: 10.2210/pdb4j4o/pdb
• Related: 2KI3 3IHZ 3NI6 4J4N
• Descriptor: 70 kDa peptidylprolyl isomerase, putative, N-(2-ethylphenyl)-2-(3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)acetamide, GLYCEROL, ... (4 entities in total)
• Functional Keywords: d44, fkbp35, fk506, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
• Biological source: Plasmodium vivax SaI-1
• Total number of polymer chains: 1
• Total formula weight: 14652.45

Authors

Sreekanth, R.,Harikishore, A.,Yoon, H.S. (deposition date: 2013-02-07, release date: 2013-09-11, Last modification date: 2023-11-08)

• Primary citation: Harikishore, A.,Niang, M.,Rajan, S.,Preiser, P.R.,Yoon, H.S.; Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent.; Sci Rep, 3:2501-2501, 2013; PubMed: 23974147; DOI: 10.1038/srep02501

Experimental method

X-RAY DIFFRACTION (1.73 Å)