4J1O

Crystal structure of an enolase (mandelate racemase subgroup) from paracococus denitrificans pd1222 (target nysgrc-012907) with bound l-proline betaine (substrate)

Summary for 4J1O

• Entry DOI: 10.2210/pdb4j1o/pdb
• Descriptor: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein, MAGNESIUM ION, IODIDE ION, ... (6 entities in total)
• Functional Keywords: enolase, betaine racemase, proline betaine racemease, nysgrc, structural genomics, new york structural genomics research consortium, psi-biology, isomerase
• Biological source: Paracoccus denitrificans
• Total number of polymer chains: 2
• Total formula weight: 85867.32

Authors

Vetting, M.W.,Toro, R.,Bhosle, R.,Wasserman, S.R.,Morisco, L.L.,Sojitra, S.,Chamala, S.,Kar, A.,LaFleur, J.,Villigas, G.,Evans, B.,Hammonds, J.,Gizzi, A.,Stead, M.,Hillerich, B.,Love, J.,Seidel, R.D.,Bonanno, J.B.,Gerlt, J.A.,Almo, S.C.,New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2013-02-01, release date: 2013-03-06, Last modification date: 2024-02-28)

• Primary citation: Kumar, R.,Zhao, S.,Vetting, M.W.,Wood, B.M.,Sakai, A.,Cho, K.,Solbiati, J.,Almo, S.C.,Sweedler, J.V.,Jacobson, M.P.,Gerlt, J.A.,Cronan, J.E.; Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine.; MBio, 5:e00933-e00913, 2014; PubMed: 24520058; DOI: 10.1128/mBio.00933-13

Experimental method

X-RAY DIFFRACTION (1.6 Å)