4J03
Crystal structure of human soluble epoxide hydrolase complexed with fulvestrant
Summary for 4J03
Entry DOI | 10.2210/pdb4j03/pdb |
Descriptor | Bifunctional epoxide hydrolase 2, PHOSPHATE ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | domain-swapped dimer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P34913 |
Total number of polymer chains | 1 |
Total formula weight | 63411.66 |
Authors | Morisseau, C.,Pakhomova, S.,Hwang, S.H.,Newcomer, M.E.,Hammock, B.D. (deposition date: 2013-01-30, release date: 2013-06-05, Last modification date: 2023-09-20) |
Primary citation | Morisseau, C.,Pakhomova, S.,Hwang, S.H.,Newcomer, M.E.,Hammock, B.D. Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorg.Med.Chem.Lett., 23:3818-3821, 2013 Cited by PubMed: 23684894DOI: 10.1016/j.bmcl.2013.04.083 PDB entries with the same primary citation |
Experimental method |
Structure validation
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