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4J03

Crystal structure of human soluble epoxide hydrolase complexed with fulvestrant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Bifunctional epoxide hydrolase 2polymer55562685.61UniProt (P34913)
Pfam (PF00702)
Pfam (PF00561)
Homo sapiens (human)Cytosolic epoxide hydrolase 2, CEH, Epoxide hydratase, Soluble epoxide hydrolase, SEH, Lipid-phosphate phosphatase
2B
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
(7beta,9beta,13alpha,17beta)-7-{9-[(R)-(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diolnon-polymer606.81Chemie (FVS)
5E
(A)
waterwater18.06Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight62685.6
Non-Polymers*Number of molecules3
Total formula weight726.0
All*Total formula weight63411.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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