4IZW

The E41L mutant of the amidase from Nesterenkonia sp. AN1 showing covalent addition of the acetamide moiety of fluoroacetamide at the active site cysteine

4IZW の概要

• エントリーDOI: 10.2210/pdb4izw/pdb
• 関連するPDBエントリー: 3HKX 4IZS 4IZT 4IZU 4IZV
• 分子名称: Amidase, ACETAMIDE, 2-fluoroacetamide, ... (4 entities in total)
• 機能のキーワード: active site, fluoroacetamide, acetamide, hydrolase
• 由来する生物種: Nesterenkonia sp. 10004
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30375.04

構造登録者

Kimani, S.W.,Sewell, B.T. (登録日: 2013-01-30, 公開日: 2014-02-12)

• 主引用文献: Kimani, S.W.,Hunter, R.,Vlok, M.,Watermeyer, J.,Sewell, B.T.; Covalent modifications of the active site cysteine occur as a result of mutating the glutamate of the catalytic triad in the amidase from Nesterenkonia sp.; To be Published,

実験手法

X-RAY DIFFRACTION (1.6 Å)