4IZT
The E41Q mutant of the amidase from Nesterenkonia sp. AN1 showing covalent addition of the acetamide moiety of fluoroacetamide at the active site cysteine
Summary for 4IZT
Entry DOI | 10.2210/pdb4izt/pdb |
Related | 3HKX 4IZS 4IZU 4IZV 4IZW |
Descriptor | Amidase, ACETAMIDE, 2-fluoroacetamide, ... (4 entities in total) |
Functional Keywords | fluoroacetamide, acetamide, hydrolase-substrate complex, hydrolase/substrate |
Biological source | Nesterenkonia sp. 10004 |
Total number of polymer chains | 1 |
Total formula weight | 30312.95 |
Authors | |
Primary citation | Kimani, S.W.,Hunter, R.,Vlok, M.,Watermeyer, J.,Sewell, B.T. Covalent modifications of the active site cysteine occur as a result of mutating the glutamate of the catalytic triad in the amidase from Nesterenkonia sp. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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