4IU4
Crystal structure of Leishmania mexicana arginase in complex with inhibitor BEC
Summary for 4IU4
Entry DOI | 10.2210/pdb4iu4/pdb |
Related | 1WVA 3GMZ 4IU0 4IU1 4IU5 |
Descriptor | Arginase, MANGANESE (II) ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | arginase fold, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Leishmania mexicana |
Total number of polymer chains | 1 |
Total formula weight | 36524.59 |
Authors | D'Antonio, E.L.,Ullman, B.,Roberts, S.C.,Gaur Dixit, U.,Wilson, M.E.,Hai, Y.,Christianson, D.W. (deposition date: 2013-01-19, release date: 2013-01-30, Last modification date: 2023-09-20) |
Primary citation | D'Antonio, E.L.,Ullman, B.,Roberts, S.C.,Dixit, U.G.,Wilson, M.E.,Hai, Y.,Christianson, D.W. Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections. Arch.Biochem.Biophys., 535:163-176, 2013 Cited by PubMed: 23583962DOI: 10.1016/j.abb.2013.03.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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