4IU4

Crystal structure of Leishmania mexicana arginase in complex with inhibitor BEC

Summary for 4IU4

Entry DOI	10.2210/pdb4iu4/pdb
Related	1WVA 3GMZ 4IU0 4IU1 4IU5
Descriptor	Arginase, MANGANESE (II) ION, GLYCEROL, ... (6 entities in total)
Functional Keywords	arginase fold, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Leishmania mexicana
Total number of polymer chains	1
Total formula weight	36524.59
Authors	D'Antonio, E.L.,Ullman, B.,Roberts, S.C.,Gaur Dixit, U.,Wilson, M.E.,Hai, Y.,Christianson, D.W. (deposition date: 2013-01-19, release date: 2013-01-30, Last modification date: 2023-09-20)
Primary citation	D'Antonio, E.L.,Ullman, B.,Roberts, S.C.,Dixit, U.G.,Wilson, M.E.,Hai, Y.,Christianson, D.W. Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections. Arch.Biochem.Biophys., 535:163-176, 2013 Cited by PubMed: 23583962 DOI: 10.1016/j.abb.2013.03.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation