4ITL
Crystal structure of LpxK from Aquifex aeolicus in complex with AMP-PCP at 2.1 angstrom resolution
Summary for 4ITL
Entry DOI | 10.2210/pdb4itl/pdb |
Related | 4EHW 4EHX 4EHY |
Descriptor | Tetraacyldisaccharide 4'-kinase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, GLYCEROL, ... (4 entities in total) |
Functional Keywords | membrane protein, kinase, lipid a, p-loop, p-loop containing nucleoside triphosphate hydrolase, disaccharide-1-phosphate 4'-kinase, membrane, transferase, lipid metabolism, tetraacyldisaccharide 4'-kinase |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 1 |
Total formula weight | 37379.22 |
Authors | Emptage, R.P.,Pemble IV, C.W.,York, J.D.,Raetz, C.R.H.,Zhou, P. (deposition date: 2013-01-18, release date: 2013-04-03, Last modification date: 2023-09-20) |
Primary citation | Emptage, R.P.,Pemble, C.W.,York, J.D.,Raetz, C.R.,Zhou, P. Mechanistic Characterization of the Tetraacyldisaccharide-1-phosphate 4'-Kinase LpxK Involved in Lipid A Biosynthesis. Biochemistry, 52:2280-2290, 2013 Cited by PubMed: 23464738DOI: 10.1021/bi400097z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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