4ITC

Crystal Structure Analysis of the K1 Cleaved Adhesin domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis W83

Summary for 4ITC

• Entry DOI: 10.2210/pdb4itc/pdb
• Related: 3KM5 3M1H
• Descriptor: Lys-gingipain W83, CALCIUM ION, GUANIDINE, ... (5 entities in total)
• Functional Keywords: beta sandwich, cleaved adhesin family, lys-gingipain, hemagglutinin domain, cell invasion, cysteine protease, calcium binding, membrane surface, hydrolase
• Biological source: Porphyromonas gingivalis
• Cellular location: Lys-gingipain catalytic subunit: Secreted, extracellular space . 39 kDa adhesin: Secreted, extracellular space . 15 kDa adhesin: Secreted, extracellular space . 44 kDa adhesin: Secreted, extracellular space : Q51817
• Total number of polymer chains: 1
• Total formula weight: 18990.95

Authors

Ganuelas, L.A.,Li, N.,Hunter, N.,Collyer, C.A. (deposition date: 2013-01-18, release date: 2013-09-25, Last modification date: 2023-09-20)

• Primary citation: Ganuelas, L.A.,Li, N.,Yun, P.,Hunter, N.,Collyer, C.A.; The lysine gingipain adhesin domains from Porphyromonas gingivalis interact with erythrocytes and albumin: Structures correlate to function.; Eur J Microbiol Immunol (Bp), 3:152-162, 2013; PubMed: 24265933; DOI: 10.1556/EuJMI.3.2013.3.2

Experimental method

X-RAY DIFFRACTION (1.55 Å)