4IS5

Crystal Structure of the ligand-free inactive Matriptase

Summary for 4IS5

Entry DOI	10.2210/pdb4is5/pdb
Related	4ISL 4ISN 4ISO
Descriptor	Suppressor of tumorigenicity 14 protein, SULFATE ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	beta barrel, serine protease, epithelium, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Membrane ; Single-pass type II membrane protein : Q9Y5Y6
Total number of polymer chains	1
Total formula weight	27429.64
Authors	Huang, M.D.,Zhao, B.Y.,Yuan, C.,Li, R. (deposition date: 2013-01-16, release date: 2013-03-06, Last modification date: 2023-09-20)
Primary citation	Zhao, B.,Yuan, C.,Li, R.,Qu, D.,Huang, M.,Ngo, J.C. Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288:11155-11164, 2013 Cited by PubMed: 23443661 DOI: 10.1074/jbc.M113.454611 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.48 Å)

Structure validation