4IS5
Crystal Structure of the ligand-free inactive Matriptase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Suppressor of tumorigenicity 14 protein | polymer | 241 | 26461.8 | 1 | UniProt (Q9Y5Y6) Pfam (PF00089) In PDB | Homo sapiens (human) | Matriptase, Membrane-type serine protease 1, MT-SP1, Prostamin, Serine protease 14, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | A | GLUTATHIONE | non-polymer | 307.3 | 1 | Chemie (GSH) | |||
| 5 | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
A: 16 - 244 (UniProt: Q9Y5Y6)
| PDB | External Database | Details |
|---|---|---|
| Gln 164 | Asn 772 | engineered mutation |
| Ala 195 | Ser 805 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26461.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 967.9 | |
| All* | Total formula weight | 27429.6 |
