4IRQ
Crystal structure of catalytic domain of human beta1,4galactosyltransferase 7 in closed conformation in complex with manganese and UDP
Summary for 4IRQ
Entry DOI | 10.2210/pdb4irq/pdb |
Related | 3LW6 4IRP |
Descriptor | Beta-1,4-galactosyltransferase 7, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | gt-a fold, closed conformation, manganese and udp complex, glycosyltransferase, golgi, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: Q9UBV7 |
Total number of polymer chains | 4 |
Total formula weight | 119190.06 |
Authors | Tsutsui, Y.,Ramakrishnan, B.,Qasba, P.K. (deposition date: 2013-01-15, release date: 2013-09-25, Last modification date: 2023-09-20) |
Primary citation | Tsutsui, Y.,Ramakrishnan, B.,Qasba, P.K. Crystal structures of beta-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding. J.Biol.Chem., 288:31963-31970, 2013 Cited by PubMed: 24052259DOI: 10.1074/jbc.M113.509984 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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