4IRQ
Crystal structure of catalytic domain of human beta1,4galactosyltransferase 7 in closed conformation in complex with manganese and UDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-1,4-galactosyltransferase 7 | polymer | 251 | 29216.3 | 4 | UniProt (Q9UBV7) Pfam (PF13733) Pfam (PF02709) | Homo sapiens (human) | Beta-1,4-GalTase 7, Beta4Gal-T7, b4Gal-T7, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7, Xylosylprotein 4-beta-galactosyltransferase, Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I, UDP-galactose:beta-xylose beta-1,4-galactosyltransferase, XGPT, XGalT-1, Xylosylprotein beta-1,4-galactosyltransferase |
| 2 | E, H, K, N (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | F, I, L, O (A, B, C, D) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) | |||
| 4 | G, J, M, P (A, B, C, D) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 4 | Chemie (TRS) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 81 - 327 (UniProt: Q9UBV7)
| PDB | External Database | Details |
|---|---|---|
| Gly 77 | - | expression tag |
| Ser 78 | - | expression tag |
| Asp 79 | - | expression tag |
| Ile 80 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116865.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2325.0 | |
| All* | Total formula weight | 119190.1 |
