4IQX
Mutant P44S P169S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
Summary for 4IQX
Entry DOI | 10.2210/pdb4iqx/pdb |
Related | 3NKY 3NL0 3NMA |
Descriptor | 3D polymerase, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*C)-3'), ... (4 entities in total) |
Functional Keywords | close right hand conformation, rna-dependent rna polymerase, 3d polymerase, transferase-dna complex, transferase/dna |
Biological source | Foot-and-mouth disease virus - type C More |
Cellular location | Picornain 3C: Host cytoplasm (By similarity): Q9QCE4 |
Total number of polymer chains | 3 |
Total formula weight | 57878.65 |
Authors | Ferrer-Orta, C.,Verdaguer, N.,Agudo, R.,Perez-Luque, R. (deposition date: 2013-01-14, release date: 2013-02-06, Last modification date: 2024-02-28) |
Primary citation | Agudo, R.,Ferrer-Orta, C.,Arias, A.,de la Higuera, I.,Perales, C.,Perez-Luque, R.,Verdaguer, N.,Domingo, E. A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6:e1001072-e1001072, 2010 Cited by PubMed: 20865120DOI: 10.1371/journal.ppat.1001072 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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