4IPA

Structure of a thermophilic Arx1

Summary for 4IPA

• Entry DOI: 10.2210/pdb4ipa/pdb
• Related: 2Q8K
• Descriptor: Putative curved DNA-binding protein, SULFATE ION (3 entities in total)
• Functional Keywords: map, methionine aminopeptidase, ribosome biogenesis, hydrolase
• Biological source: Chaetomium thermophilum var. thermophilum DSM 1495
• Total number of polymer chains: 4
• Total formula weight: 187445.39

Authors

Bange, G.,Sinning, I. (deposition date: 2013-01-09, release date: 2013-01-30, Last modification date: 2023-09-20)

Primary citation

van Noort, V.,Bradatsch, B.,Arumugam, M.,Amlacher, S.,Bange, G.,Creevey, C.,Falk, S.,Mende, D.R.,Sinning, I.,Hurt, E.,Bork, P.
Consistent mutational paths predict eukaryotic thermostability.
BMC Evol Biol, 13:7-7, 2013

PubMed Abstract: Proteomes of thermophilic prokaryotes have been instrumental in structural biology and successfully exploited in biotechnology, however many proteins required for eukaryotic cell function are absent from bacteria or archaea. With Chaetomium thermophilum, Thielavia terrestris and Thielavia heterothallica three genome sequences of thermophilic eukaryotes have been published.

PubMed: 23305080
DOI: 10.1186/1471-2148-13-7

Experimental method

X-RAY DIFFRACTION (2.3 Å)