4IMO

Crystal structure of wild type human Lipocalin PGDS in complex with substrate analog U44069

Summary for 4IMO

Entry DOI	10.2210/pdb4imo/pdb
Related	4IMN
Descriptor	Lipocalin-type prostaglandin-D synthase, (5E)-7-{(1R,4S,5S,6R)-5-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-6-yl}hept-5-enoic acid, THIOCYANATE ION, ... (4 entities in total)
Functional Keywords	beta barrel, isomerase, endoplasmic reticulum
Biological source	Homo sapiens (human)
Cellular location	Rough endoplasmic reticulum: P41222
Total number of polymer chains	1
Total formula weight	20565.29
Authors	Lim, S.M.,Chen, D.,Teo, H.,Roos, A.,Nyman, T.,Tresaugues, L.,Pervushin, K.,Nordlund, P. (deposition date: 2013-01-03, release date: 2013-03-20, Last modification date: 2023-09-20)
Primary citation	Lim, S.M.,Chen, D.,Teo, H.,Roos, A.,Jansson, A.E.,Nyman, T.,Tresaugues, L.,Pervushin, K.,Nordlund, P. Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase. J.Lipid Res., 54:1630-1643, 2013 Cited by PubMed: 23526831 DOI: 10.1194/jlr.M035410 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation