4IM3
Structure of Tank-Binding Kinase 1
Summary for 4IM3
Entry DOI | 10.2210/pdb4im3/pdb |
Related | 4IM0 4IM2 |
Descriptor | Serine/threonine-protein kinase TBK1, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, MERCURY (II) ION, ... (4 entities in total) |
Functional Keywords | kinase, serine/threonine kinase, bx795, pcmnp, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 77814.93 |
Authors | |
Primary citation | Tu, D.,Zhu, Z.,Zhou, A.Y.,Yun, C.H.,Lee, K.E.,Toms, A.V.,Li, Y.,Dunn, G.P.,Chan, E.,Thai, T.,Yang, S.,Ficarro, S.B.,Marto, J.A.,Jeon, H.,Hahn, W.C.,Barbie, D.A.,Eck, M.J. Structure and ubiquitination-dependent activation of TANK-binding kinase 1. Cell Rep, 3:747-758, 2013 Cited by PubMed: 23453972DOI: 10.1016/j.celrep.2013.01.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.342 Å) |
Structure validation
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