4ILW
Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-2 (TIMP-2)
Summary for 4ILW
Entry DOI | 10.2210/pdb4ilw/pdb |
Descriptor | Metalloproteinase inhibitor 2, Stromelysin-2, ZINC ION, ... (5 entities in total) |
Functional Keywords | metzincin, ob-fold, metalloproteinase, protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P16035 Secreted, extracellular space, extracellular matrix (Probable): P09238 |
Total number of polymer chains | 4 |
Total formula weight | 81209.30 |
Authors | Batra, J.,Soares, A.S.,Radisky, E.S. (deposition date: 2013-01-01, release date: 2013-11-13, Last modification date: 2023-09-20) |
Primary citation | Batra, J.,Soares, A.S.,Mehner, C.,Radisky, E.S. Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes. Plos One, 8:e75836-e75836, 2013 Cited by PubMed: 24073280DOI: 10.1371/journal.pone.0075836 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.103 Å) |
Structure validation
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