4IHO
Crystal structure of H-2Db Y159F in complex with chimeric gp100
Summary for 4IHO
Entry DOI | 10.2210/pdb4iho/pdb |
Related | 3CCH 3CH1 |
Descriptor | H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, NONAMERIC PEPTIDE CHIMERIC GP100, ... (6 entities in total) |
Functional Keywords | mhc, h-2db, glycoprotein, immune response, mhc i, transmembrane, immunoglobulin domain, disease mutation, melanoma, immune system, tumor associated antigen, altered peptide ligand, t cell receptor |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01899 Secreted: P01887 |
Total number of polymer chains | 6 |
Total formula weight | 90154.82 |
Authors | Uchtenhagen, H.,Stahl, E.,Achour, A. (deposition date: 2012-12-19, release date: 2013-09-11, Last modification date: 2023-11-08) |
Primary citation | Uchtenhagen, H.,Abualrous, E.T.,Stahl, E.,Allerbring, E.B.,Sluijter, M.,Zacharias, M.,Sandalova, T.,van Hall, T.,Springer, S.,Nygren, P.A.,Achour, A. Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides Eur.J.Immunol., 43:3051-3060, 2013 Cited by PubMed: 23939911DOI: 10.1002/eji.201343456 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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