4IH8

Crystal structure of TgCDPK1 with inhibitor bound

Summary for 4IH8

• Entry DOI: 10.2210/pdb4ih8/pdb
• Descriptor: Calmodulin-domain protein kinase 1, 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane (3 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Toxoplasma gondii
• Total number of polymer chains: 1
• Total formula weight: 57703.48

Authors

El Bakkouri, M.,Tempel, W.,Crandall, I.,Massad, T.,Loppnau, P.,Graslund, S.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Kain, K.,Hui, R.,Structural Genomics Consortium (SGC) (deposition date: 2012-12-18, release date: 2014-04-16, Last modification date: 2024-02-28)

• Primary citation: El Bakkouri, M.,Tempel, W.,Crandall, I.,Massad, T.,Loppnau, P.,Graslund, S.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Kain, K.,Hui, R.,Structural Genomics Consortium (SGC); Crystal structure of TgCDPK1 with inhibitor bound; To be Published,

Experimental method

X-RAY DIFFRACTION (2.877 Å)