4IB3

Structure of cAMP dependent protein kinase A in complex with ADP, phosphorylated peptide pSP20, and no metal

4IB3 の概要

• エントリーDOI: 10.2210/pdb4ib3/pdb
• 関連するPDBエントリー: 4IAC 4IAD 4IAF 4IAI 4IAK 4IAY 4IAZ 4IB0 4IB1
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, phosphorylated pseudo-substrate peptide pSP20, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: kinase enzyme, phosphotransfer, phosphorylated, transferase-peptide complex, transferase/peptide
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm. Isoform 2: Cell projection, cilium, flagellum (By similarity): P05132
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44272.74

構造登録者

Gerlits, O.,Kovalevsky, A. (登録日: 2012-12-07, 公開日: 2013-12-11, 最終更新日: 2014-05-28)

• 主引用文献: Gerlits, O.,Das, A.,Keshwani, M.M.,Taylor, S.,Waltman, M.J.,Langan, P.,Heller, W.T.,Kovalevsky, A.; Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.; Biochemistry, 53:3179-3186, 2014; PubMed: 24786636; DOI: 10.1021/bi5000965

実験手法

X-RAY DIFFRACTION (2.2 Å)