4IAA

Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine

Summary for 4IAA

• Entry DOI: 10.2210/pdb4iaa/pdb
• Descriptor: Serine/threonine-protein kinase pim-1, 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine (3 entities in total)
• Functional Keywords: pim1 kinase/oncogene/thioridazine, ser/thr kinase, thioridazine, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309
• Total number of polymer chains: 1
• Total formula weight: 33663.29

Authors

Zhang, W.,Wan, X.,Li, W.,Xie, Y.,Huang, N. (deposition date: 2012-12-06, release date: 2013-12-18)

• Primary citation: Zhang, W.,Wan, X.,Li, W.,Xie, Y.,Huang, N.; Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine; To be Published,

Experimental method

X-RAY DIFFRACTION (2.85 Å)