4I9X

Crystal structure of human cytomegalovirus glycoprotein UL141 targeting the death receptor TRAIL-R2

Summary for 4I9X

Entry DOI	10.2210/pdb4i9x/pdb
Descriptor	Protein UL141, Tumor necrosis factor receptor superfamily member 10B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	ig-like domain, apoptosis
Biological source	Human herpesvirus 5 (HHV-5) More
Cellular location	Host endoplasmic reticulum membrane; Single- pass membrane protein: Q6RJQ3 Membrane; Single-pass type I membrane protein: O14763
Total number of polymer chains	4
Total formula weight	80127.38
Authors	Nemcovicova, I.,Zajonc, D.M. (deposition date: 2012-12-05, release date: 2013-04-03, Last modification date: 2020-07-29)
Primary citation	Nemcovicova, I.,Benedict, C.A.,Zajonc, D.M. Structure of Human Cytomegalovirus UL141 Binding to TRAIL-R2 Reveals Novel, Non-canonical Death Receptor Interactions. Plos Pathog., 9:e1003224-e1003224, 2013 Cited by PubMed: 23555243 DOI: 10.1371/journal.ppat.1003224 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation