4I9V

The atomic structure of 5-Hydroxymethyl 2'-deoxycitidine base paired with 2'-deoxyguanosine in Dickerson Drew Dodecamer

4I9V の概要

• エントリーDOI: 10.2210/pdb4i9v/pdb
• 関連するPDBエントリー: 355D
• 分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(5HC)P*GP*CP*G)-3'), MAGNESIUM ION, SPERMINE (FULLY PROTONATED FORM), ... (4 entities in total)
• 機能のキーワード: 5-hydroxymethyl 2' deoxycitidine, 5-hydroxymethyl-dc adduct, modified ddd, dodecamer of b-dna, dna
• 由来する生物種: Synthetic DNA
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7823.89

構造登録者

Nocek, B.,Szulik, M.W.,Joachimiak, A.,Stone, M.P. (登録日: 2012-12-05, 公開日: 2013-11-20, 最終更新日: 2023-09-20)

• 主引用文献: Szulik, M.W.,Pallan, P.S.,Nocek, B.,Voehler, M.,Banerjee, S.,Brooks, S.,Joachimiak, A.,Egli, M.,Eichman, B.F.,Stone, M.P.; Differential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine.; Biochemistry, 54:1294-1305, 2015; PubMed: 25632825; DOI: 10.1021/bi501534x

実験手法

X-RAY DIFFRACTION (1.02 Å)