4I8A
Alanine-glyoxylate aminotransferase variant S187F
Summary for 4I8A
Entry DOI | 10.2210/pdb4i8a/pdb |
Related | 1H0C 1JO4 |
Descriptor | Serine-pyruvate aminotransferase, GLYCEROL (2 entities in total) |
Functional Keywords | aminotransferase, primary hyperoxaluria type 1, peroxisome, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Peroxisome: P21549 |
Total number of polymer chains | 4 |
Total formula weight | 175113.94 |
Authors | Fodor, K.,Oppici, E.,Williams, C.,Cellini, B.,Wilmanns, M. (deposition date: 2012-12-03, release date: 2013-05-01, Last modification date: 2023-12-06) |
Primary citation | Oppici, E.,Fodor, K.,Paiardini, A.,Williams, C.,Voltattorni, C.B.,Wilmanns, M.,Cellini, B. Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications. Proteins, 81:1457-1465, 2013 Cited by PubMed: 23589421DOI: 10.1002/prot.24300 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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