4I7H

Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes

4I7H の概要

• エントリーDOI: 10.2210/pdb4i7h/pdb
• 分子名称: peroxide stress sensing regulator, NICKEL (II) ION, ZINC ION, ... (4 entities in total)
• 機能のキーワード: winged helix-turn-helix motif, oxidative stress sensing, metal homeostasis, dna, transcription
• 由来する生物種: Streptococcus pyogenes
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38046.94

構造登録者

Kumaraswami, M. (登録日: 2012-11-30, 公開日: 2013-05-08, 最終更新日: 2024-02-28)

• 主引用文献: Makthal, N.,Rastegari, S.,Sanson, M.,Ma, Z.,Olsen, R.J.,Helmann, J.D.,Musser, J.M.,Kumaraswami, M.; Crystal Structure of Peroxide Stress Regulator from Streptococcus pyogenes Provides Functional Insights into the Mechanism of Oxidative Stress Sensing.; J.Biol.Chem., 288:18311-18324, 2013; PubMed: 23645680; DOI: 10.1074/jbc.M113.456590

実験手法

X-RAY DIFFRACTION (2 Å)