4I6L
Crystal structure of OTUB1 in complex with ubiquitin variant
Summary for 4I6L
Entry DOI | 10.2210/pdb4i6l/pdb |
Descriptor | Ubiquitin thioesterase OTUB1, Ubiquitin (3 entities in total) |
Functional Keywords | deubiquitinase, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (By similarity): Q96FW1 Ubiquitin: Cytoplasm (By similarity): P0CG48 |
Total number of polymer chains | 2 |
Total formula weight | 35332.88 |
Authors | Juang, Y.C.,Sicheri, F. (deposition date: 2012-11-29, release date: 2013-01-16, Last modification date: 2023-09-20) |
Primary citation | Ernst, A.,Avvakumov, G.,Tong, J.,Fan, Y.,Zhao, Y.,Alberts, P.,Persaud, A.,Walker, J.R.,Neculai, A.M.,Neculai, D.,Vorobyov, A.,Garg, P.,Beatty, L.,Chan, P.K.,Juang, Y.C.,Landry, M.C.,Yeh, C.,Zeqiraj, E.,Karamboulas, K.,Allali-Hassani, A.,Vedadi, M.,Tyers, M.,Moffat, J.,Sicheri, F.,Pelletier, L.,Durocher, D.,Raught, B.,Rotin, D.,Yang, J.,Moran, M.F.,Dhe-Paganon, S.,Sidhu, S.S. A strategy for modulation of enzymes in the ubiquitin system. Science, 339:590-595, 2013 Cited by PubMed: 23287719DOI: 10.1126/science.1230161 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.488 Å) |
Structure validation
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