4I1P

Human MALT1 (caspase-IG3) in complex with activity based-probe

Summary for 4I1P

Entry DOI	10.2210/pdb4i1p/pdb
Related	4I1R
Descriptor	Mucosa-associated lymphoid tissue lymphoma translocation protein 1, tetrapeptide, ACETATE ION, ... (4 entities in total)
Functional Keywords	protease, hydrolase
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, perinuclear region : Q9UDY8
Total number of polymer chains	4
Total formula weight	90469.88
Authors	Schlauderer, F.,Lammens, K.,Hopfner, K.P. (deposition date: 2012-11-21, release date: 2014-07-09, Last modification date: 2023-11-15)
Primary citation	Eitelhuber, A.C.,Vosyka, O.,Nagel, D.,Bognar, M.,Lenze, D.,Lammens, K.,Schlauderer, F.,Hlahla, D.,Hopfner, K.P.,Lenz, G.,Hummel, M.,Verhelst, S.H.,Krappmann, D. Activity-Based Probes for Detection of Active MALT1 Paracaspase in Immune Cells and Lymphomas. Chem.Biol., 22:129-138, 2015 Cited by PubMed: 25556945 DOI: 10.1016/j.chembiol.2014.10.021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.403 Å)

Structure validation