4HX6
Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6
Summary for 4HX6
Entry DOI | 10.2210/pdb4hx6/pdb |
Related | 4OO2 4R82 |
Descriptor | Oxidoreductase, SULFATE ION, ACETATE ION, ... (4 entities in total) |
Functional Keywords | structural genomics, psi-biology, protein structure initiative, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, oxidoreductase |
Biological source | Streptomyces globisporus |
Total number of polymer chains | 8 |
Total formula weight | 160471.17 |
Authors | Tan, K.,Bigelow, L.,Clancy, S.,Babnigg, G.,Bingman, C.A.,Yennamalli, R.,Lohman, J.R.,Ma, M.,Shen, B.,Phillips Jr., G.N.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2012-11-09, release date: 2012-11-28, Last modification date: 2016-12-07) |
Primary citation | Chang, C.Y.,Lohman, J.R.,Cao, H.,Tan, K.,Rudolf, J.D.,Ma, M.,Xu, W.,Bingman, C.A.,Yennamalli, R.M.,Bigelow, L.,Babnigg, G.,Yan, X.,Joachimiak, A.,Phillips, G.N.,Shen, B. Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55:5142-5154, 2016 Cited by PubMed: 27560143DOI: 10.1021/acs.biochem.6b00713 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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