4HSH

tRNA-guanine transglycosylase Y106F, V233G mutant in complex with queuine

Summary for 4HSH

Entry DOI	10.2210/pdb4hsh/pdb
Related	3BLO 4E2V 4GCX 4GD0 4H6E 4H7Z 4HQV
Descriptor	Queuine tRNA-ribosyltransferase, GLYCEROL, ZINC ION, ... (5 entities in total)
Functional Keywords	substrate specificity, bacterial tgt, transferase, guanine, preq1, queuine, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Zymomonas mobilis subsp. mobilis
Total number of polymer chains	1
Total formula weight	43723.78
Authors	Biela, I.,Tidten-Luksch, N.,Heine, A.,Reuter, K.,Klebe, G. (deposition date: 2012-10-30, release date: 2012-11-28, Last modification date: 2023-09-20)
Primary citation	Biela, I.,Tidten-Luksch, N.,Immekus, F.,Glinca, S.,Nguyen, T.X.,Gerber, H.D.,Heine, A.,Klebe, G.,Reuter, K. Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8:e64240-e64240, 2013 Cited by PubMed: 23704982 DOI: 10.1371/journal.pone.0064240 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.56 Å)

Structure validation