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4HSH

tRNA-guanine transglycosylase Y106F, V233G mutant in complex with queuine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Queuine tRNA-ribosyltransferasepolymer38542736.41UniProt (P28720)
Pfam (PF01702)
Zymomonas mobilis subsp. mobilisGuanine insertion enzyme, tRNA-guanine transglycosylase
2B, D, E, F, G...
(A)
GLYCEROLnon-polymer92.17Chemie (GOL)
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4J
(A)
2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-onenon-polymer277.31Chemie (QEI)
5K
(A)
waterwater18.0318Chemie (HOH)
Sequence modifications
A: 2 - 386 (UniProt: P28720)
PDBExternal DatabaseDetails
Phe 106Tyr 106engineered mutation
Gly 233Val 233engineered mutation
Lys 312Thr 312SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42736.4
Non-Polymers*Number of molecules9
Total formula weight987.3
All*Total formula weight43723.8
*Water molecules are not included.

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PDB entries from 2024-10-30

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