4HS3

Crystal structure of H-2Kb with a disulfide stabilized F pocket in complex with the LCMV derived peptide GP34

4HS3 の概要

• エントリーDOI: 10.2210/pdb4hs3/pdb
• 分子名称: H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, Envelope glycoprotein, ... (6 entities in total)
• 機能のキーワード: mhc class i, antigen presentation, antigen processing, peptide binding, igg, mhc, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01901; Secreted: P01887
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44680.14

構造登録者

Uchtenhagen, H.,Boulanger, B.,Hein, Z.,Abualrous, E.T.,Zacharias, M.,Werner, J.,Elliott, T.,Springer, S.,Achour, A. (登録日: 2012-10-29, 公開日: 2014-05-07, 最終更新日: 2023-09-20)

• 主引用文献: Hein, Z.,Uchtenhagen, H.,Abualrous, E.T.,Saini, S.K.,Janen, L.,Van Hateren, A.,Wiek, C.,Hanenberg, H.,Momburg, F.,Achour, A.,Elliott, T.,Springer, S.,Boulanger, D.; Peptide-independent stabilization of MHC class I molecules breaches cellular quality control.; J.Cell.Sci., 127:2885-2897, 2014; PubMed: 24806963; DOI: 10.1242/jcs.145334

実験手法

X-RAY DIFFRACTION (2.1 Å)