4HMZ

Crystal Structure of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP-quinovose

4HMZ の概要

• エントリーDOI: 10.2210/pdb4hmz/pdb
• 関連するPDBエントリー: 4HN0 4HN1
• 分子名称: Putative 3-epimerase in D-allose pathway, 1,2-ETHANEDIOL, [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate, ... (4 entities in total)
• 機能のキーワード: 3'-monoepimerase, natural product, deoxysugar, chalcomycin, dtdp-mycinose, dtdp-quinovose, cupin fold, nucleotide-linked sugar, epimerization, unknown function
• 由来する生物種: Streptomyces bikiniensis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 91530.73

構造登録者

Holden, H.M.,Kubiak, R.L. (登録日: 2012-10-18, 公開日: 2012-11-21, 最終更新日: 2023-09-20)

• 主引用文献: Kubiak, R.L.,Phillips, R.K.,Zmudka, M.W.,Ahn, M.R.,Maka, E.M.,Pyeatt, G.L.,Roggensack, S.J.,Holden, H.M.; Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.; Biochemistry, 51:9375-9383, 2012; PubMed: 23116432; DOI: 10.1021/bi3012737

実験手法

X-RAY DIFFRACTION (2 Å)